Catalytic Asymmetric Ylide Generation and Subsequent Transformation via Chiral Metal Carbene Intermediates.

Study on Catalytic and Asymmetric Carbene Transfer Reactions Using Chiral (Salen)cobalt(lll) Complexes

Catalytic Dibenzocyclooctene Synthesis via Cobalt(III)–Carbene Radical and ortho‐Quinodimethane Intermediates

The metalloradical activation of ortho-benzallylaryl N-tosyl hydrazones with [Co(TPP)] (TPP=tetraphenylporphyrin) as the catalyst enabled the controlled exploitation of the single-electron reactivity of the redox non-innocent carbene intermediate. This method offers a novel route to prepare eight-membered rings, using base metal catalysis to construct a series of unique dibenzocyclooctenes thro...

Chiral salen-metal derivatives of polyoxometalates with asymmetric catalytic and photocatalytic activities.

Immobilization of the chiral salen-metal complex [Mn(III)(salen)(H(2)O)(2)ClO(4)] on the Keggin-type polyoxometalate (POM) skeletons leads to the isolation of POM derivatives functionalized with chiral salen-metal complexes, which represent the first examples of introducing chiral salen-metal complexes into the POM systems.

Relay catalysis using a rhodium complex/chiral Brønsted acid binary system: enantioselective reduction of a carbonyl ylide as the reactive intermediate.

Carbonyl ylides are generally non-isolable reactive intermediates and have been extensively utilized as the dipole in 1,3-dipolar cycloaddition reactions with electron-deficient and electron-rich dipolarophiles to afford polycyclic compounds including five-membered oxacycles. The most efficient method for generating the carbonyl ylide is the interaction of a metal carbene complex with the oxyge...

Nickel(ii)-catalyzed enantioselective cyclopropanation of 3-alkenyl-oxindoles with phenyliodonium ylide via free carbene† †Electronic supplementary information (ESI) available. CCDC 1038443 and 1038445. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc03658e Click here for additional data file. Click here for additional data file.

The catalytic asymmetric cyclopropanation of a C]C double bond provides efficient access to optically active cyclopropane derivatives that are essential motifs in natural products and valuable building blocks for various transformations. Chiral transition-metal-catalyzed carbene transfer, such as that using Cu(I)-, Rh(II)-, Ru(II)-, and Co(II)-complexes with diazo compounds, permits such cylcop...